Hours after a pair of flares were fired at Prime Minister Benjamin Netanyahu's Caesarea residence, three people were arrested on Sunday morning.
The suspects are yet to be identified and no group has claimed responsibility for the act.
There was no damage to structures or injuries during the incident. Netanyahu and his family were also not home when it happened.
The Shin Bet agency and the police said an investigation has been launched and it is "a dangerous escalation."
Israeli President Isaac Herzog condemned the act, saying he has expressed urgent need to probe and deal with those responsible.
Taking to X, Israeli Defence Minister Israel Katz said the incident crossed "all red lines". "It is not possible for the Prime Minister of Israel, who is threatened by Iran and its proxies who are trying to assassinate him, to be subject to the same threats from home," he posted.
This comes less than a month after Netanyahu's Caesarea residence was targeted in a drone attack by Hezbollah. The Israeli PM and his wife were not home.
In September, Netanyahu's plane was targeted by a ballistic missile while landing at Ben Gurion Airport. The missile was intercepted.
This comes as Israeli ground troops advanced to the deepest point in Lebanon since the conflict with the northern country broke out six weeks ago.
Over 3,400 people have been killed in Lebanon, according to the country's health ministry.